Русско-англо-русский юридический словарь

A dominant position is not in itself anti-competitive, but if the company exploits this position to eliminate competition, it is considered to have abused it. (http://ec.europa.eu)

An explosive substance is a solid or liquid substance (or mixture of substances) which is in itself capable by chemical reaction of producing gas at such a temperature and pressure and at such a speed as to cause damage to the surroundings. (ILO website)

Voluntary surrender of the accused is "deemed a significant mitigating circumstance in determining the sentence". Voluntary surrender occurs rarely and is often combined with remorse, whereas a guilty plea "where entered may in itself constitute a factor substantially mitigating the sentence". (The Trial Proceedings Of The International Criminal Court: ICTY And ICTR)

in itself means "not needing other things". This deed, in itself, is an impeachable offense. (StackExchange)